WHAT IS VANCOMYCIN TEST?

WHAT IS VANCOMYCIN TEST?

Vancomycin is an aminoglycoside antibiotic that inhibits cell wall synthesis of gram-positive bacteria. It is frequently used in the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) and in treatment for pseudomembranous colitis. Vancomycin is metabolized in the liver, with 80% excreted through the kidneys and a small amount in bile. Oral doses are primarily excreted in the faeces. Vancomycin half-life is very dependent on renal glomerular function. Rapid infusions of this drug have been associated with histamine release causing “red-man syndrome,” in which the skin becomes flushed, erythematous, and pruritic. The predictability of therapeutic effect is better at trough levels than at peak levels; thus, peak levels are not routinely recommended unless the client has renal failure or in other situations where the volume distribution is increased. 

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About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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