WHAT IS THE FLUORESCENT TREPONEMAL ANTIBODY–ABSORBED DOUBLE-STAIN (FTA-ABS DS) TEST?

WHAT IS THE FLUORESCENT TREPONEMAL ANTIBODY–ABSORBED DOUBLE-STAIN (FTA-ABS DS) TEST?

Syphilis is a complex, sexually transmitted disease characterised by a wide range of symptoms that imitate other diseases and is caused by the organism Treponema pallidum. This test provides the most sensitive detection of treponemal antibodies for syphilis in all stages. It differentiates biologic false-positive results from true syphilis-positive results and can help diagnose syphilis when definite clinical signs are present, but other tests are negative. This test is positive in the treponemal diseases of bejelpinta, syphilis, and yaws. Before testing, the serum is treated to remove antibodies that could cause false-positive results. The technique involves using fluorescence microscopy with special filters that decrease the amount of natural fluorescence from the background of the specimen. Fluorescein-conjugated antibodies to IgG are added as a counterstain to the stained specimen, and the treponemes are identified as they fluoresce in combination with the antibodies. 

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Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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