WHAT IS PROPRANOLOL TEST?
Propranolol hydrochloride is a beta-adrenergic blocking drug classified as a type II cardiac antidysrhythmic. It competes with epinephrine and norepinephrine for beta-adrenergic receptors, resulting in inhibition of myocardial beta-adrenergic stimulation. Cardiac effects include reduced irritability and heart rate because the automaticity of the SA node, AV node, and intraventricular conduction velocity is depressed. Large doses depress cardiac function. Brugada syndrome may be present on ECG noted by RBBB, coved ST–segment elevation in precordial leads V1 to V3, and this increases the risk for cardiac death. Propranolol may also cause hypoglycemia without warning in diabetic clients. Propranolol is bound to plasma proteins, metabolized in the liver, and excreted in the urine, with a half-life of 2-6 hours. Steady-state levels are reached after 10-30 hours.