WHAT IS ORAL MUCOSAL TRANSUDATE (OMT, HIV ORAL TEST) TEST?

WHAT IS ORAL MUCOSAL TRANSUDATE (OMT, HIV ORAL TEST) TEST?

Oral mucosal transudate is a serous fluid that derives from transudation at the gingival crevice. The OMT method detects the presence of HIV antibodies using a micro–enzyme-linked immunosorbent assay similar to the ELISA. Samples collected are placed in a nontoxic stabilizing preservative that prevents bacterial growth and degradation of IgG by bacterial protease. Modifications in collection technology and immunosorbent assays have improved the detection of HIV-1 antibodies in oral specimens. The EpiScreen HIV-1, Oral Specimen Collection device, is currently the only FDA-approved oral HIV antibody test and is restricted to testing with the oral fluid Vironostika HIV-1 Microelisa System (Organon Teknika Corp., Durham, NC). The salivary Western blot is an in vitro qualitative assay developed specifically for oral mucosal transudate (Epitope, Inc.) The OraSure Specimen Collection Device (Epitope, Inc.) is an FDA-approved device that looks similar to a toothbrush, with a padded end that is used for collection of oral specimens for HIV testing. Oral mucosal specimens follow the algorithm recommended for blood samples by the Centers for Disease Control and Prevention. 

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About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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