WHAT IS LUPUS TEST (LE TEST, LE CELL TEST, LE PREPARATION, LE SLIDE CELL TEST, LUPUS ERYTHEMATOSUS CELL TEST, LYMPHOCYTE ERYTHEMATOUS CELL TEST)?
This is a serologic test used to diagnose SLE and to monitor its treatment. Clients with SLE have antibodies against the components of nuclei within their own cells. One usually performs this test by traumatizing white blood cells and exposing the nuclear material within them. Then the nuclear material is incubated with the client’s serum. Neutrophils in the affected client’s serum will phagocytize the traumatized nuclear material. The phagocytized complex appears as a blue-staining, amorphous mass distending the neutrophil’s cytoplasm after the cells are stained with Wright’s stain. When these neutrophils, which are now filled LE cells, are seen, the test is considered positive.