WHAT IS LACTATE DEHYDROGENASE (LD, LDH) TEST?
Lactate dehydrogenase (LD) is an intracellular enzyme found in almost all body tissues and is released after tissue damage. The highest concentrations are found in organs such as the heart, liver, kidneys, and skeletal muscle cells as well as red blood cells. When body tissue is damaged from trauma, ischemia, or acid/base imbalance, LD is released into the bloodstream. The results of this test indicate that tissue damage has occurred but cannot pinpoint the specific location of the damage. When total LD is elevated to at least 130 IU/L, the test Lactate Dehydrogenase Isoenzymes— Blood should be performed to narrow down the source of tissue damage.