WHAT IS KETONE (SEMIQUANTITATIVE) TEST?
Ketone bodies consist of acetoacetic acid, beta-hydroxybutyric acid, and acetone and are by-products of fat and fatty acid metabolism. In a low-insulin state such as diabetes, fat and fatty acids are metabolized less efficiently than normal, resulting in a buildup of serum ketones. Elevated serum ketones are excreted through the kidneys into the urine. In this test, a dipstick is used for determining ketones in the urine. The reagent strip correlates only moderately well with quantitative acetoacetate in plasma and poorly with total blood ketones but is a better screening test for diabetic ketoacidosis than the anion gap or serum bicarbonate tests. Semiquantitative results mean testing several different dilutions of each urine specimen to obtain a better degree of differentiation of ketone body products that can be obtained from qualitative testing.