WHAT IS HUMAN LEUKOCYTE ANTIGEN (HLA) TYPING (TISSUE TYPING) TEST?

WHAT IS HUMAN LEUKOCYTE ANTIGEN (HLA) TYPING (TISSUE TYPING) TEST?

Human leukocyte antigens (HLAs) are glycoproteins found on all nucleated cells. They result from four closely linked genes on chromosome 6 and are important to histocompatibility complement and immune response. The antigens are divided into A, B, C (Class I, derived from T cells), D, and DR (D-related, Class II, derived from B cells). There are multiple antigens of each type, meaning that the combinations of antigens that identify any individual are infinite. The HLAs are inherited as two sets (one from each parent) of six antigens. This test is most commonly used in the bone marrow and renal transplantation. The antigens must match for transplantation to occur without organ rejection. 

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About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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