WHAT IS HOMOVANILLIC ACID (HVA) TEST?
Homovanillic acid is the major terminal metabolite of dopamine, one of the three catecholamines produced in the brain. Dopamine is broken down by the liver and excreted in the urine as homovanillic acid. Elevated levels can occur as a result of catecholamine-secreting tumours. Because urinary HVA levels fluctuate with creatinine excretion, results are normalized to the amount of creatinine present in the urine sample.