WHAT IS GHRELIN TEST?
Ghrelin is a growth hormone–releasing peptide found in the stomach and in many other organs and tissues throughout the body. This peptide’s function in the stomach is best understood, but its function throughout the rest of the body is still being studied. Ghrelin levels have been shown to increase before meals, causing an increase in glucose level, which increases the appetite. Ghrelin also stimulates the release of insulin from the islet cells of the pancreas. Ghrelin levels decrease after meals, possibly in response to increased plasma glucose. In those on weight-reduction diets, Ghrelin baseline levels have been found to increase (Cummings et al, 2002). This effect indicates a potential role of Ghrelin in weight regain experienced by many dieters. Other effects of Ghrelin include stimulating the release of adrenocorticotropic hormone, epinephrine, and glucose.