WHAT IS FACTOR XIII (FIBRIN-STABILIZING FACTOR, CLOT UREA SOLUBILITY) TEST?

WHAT IS FACTOR XIII (FIBRIN-STABILIZING FACTOR, CLOT UREA SOLUBILITY) TEST?

Factor XIII is an alpha globulin that, in its active form, stabilises fibrin clots. Its deficiency is a rare, inherited, autosomal recessive condition that may result in symptoms ranging from abnormal bleeding from cuts and bleeding in joints to cerebral haemorrhage and infant death from umbilical cord haemorrhage. One performs the test by adding calcium chloride to the sample and clotting the mixture at 37 degrees C for an hour, and then placing the clot in 5 M urea and observing hourly for clot dissolution. Clots from clients with factor XIII deficiency will dissolve within 1-3 hours. 

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About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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