WHAT IS CYTOMEGALOVIRUS ANTIBODY TEST?
Cytomegalovirus is a herpesvirus. The virus is present in a large segment of the population early in life without causing apparent disease. Serologic prevalence studies show that 60%-90% of U.S. adults, depending on a socioeconomic level, and very old people are positive for antibodies to CMV. Because the presence of the disease is unusual, host factors predisposing to the disease should be investigated when the disease is manifested. CMV mononucleosis usually occurs in older adults, compared to Epstein-Barr mononucleosis, and presents with a lower incidence of pharyngitis and lymphadenopathy. Congenital CMV may cause a variety of developmental abnormalities and neurologic deficits in the infant or young child. In the immunosuppressed client, pulmonary or systemic infections may occur. Clients receiving tissue transplants (liver, heart, lung, kidney, and bone) are also at high risk for manifested infections. CMV immune status should be performed on all organ transplant candidates before surgery. Blood for transfusion to seronegative transplant clients and all premature neonates should be from donors without CMV antibodies.