WHAT IS CLOSTRIDIAL TOXIN TEST?
Clostridia are gram-positive anaerobes of the family Bacillaceae characterised by the production of exothermic spores, enzymes, and potent endotoxins. Clostridium species are found in soil, freshwater, and marine sediments, and some species are part of the human lower gastrointestinal tract. C. botulinum causes botulism, a neuroparalytic disease transmitted by the clostridial spores that survive improper cooking of food. Botulism causes acute flaccid paralysis and may lead to death if not treated with antitoxin before the onset of neurologic symptoms. Infant botulism is represented by hypotonia, feeding disruption, and a weak cry. Because of the severity of the disease and the potential for an epidemic among other clients ingesting the affected food, cases of suspected botulism must be immediately reported to the state department of health and the Centers for Disease Control and Prevention. Serum samples are used to confirm the diagnosis by identification of the toxin of C. botulinum.