WHAT IS C. DIFFICILE AMPLIFIED PROBE TEST?
A rapid method of identifying the C. difficile toxin using polymerase chain reaction (Goldenberg, 2010) that amplifies the presence of known nucleotides until there are enough copies present to be detectable by standard laboratory methods. This test provides more rapid results than standard enzyme immunoassay testing and provides higher sensitivity, but comparable specificity. However, it is unclear whether the accuracy of the results is improved. This test is four times more expensive to perform than standard enzyme immunoassay testing, and evidence is lacking regarding whether the faster speed of obtaining results leads to better clinical outcomes.