WHAT IS ALPHA1-ANTITRYPSIN TEST?
A major faction of alpha1-globulin protein detected by serum protein immunoelectrophoresis. Alpha1-antitrypsin is a serine proteinase inhibitor that functions in the protection of body fluids by inactivating neutrophil elastase, a byproduct of lung inflammatory or infectious processes. The test is used to screen for clients at high risk for emphysema and liver disease associated with a congenital absence of the protein. Clients who have symptoms of cough, dyspnea or wheezing, in conjunction with a smoking history, should be evaluated for COPD using this test and spirometry. Other uses for this test include nonspecific detection of inflammatory, infectious, and necrotic processes.