WHAT IS ALPHA-FETOPROTEIN (AFP) TEST?

WHAT IS ALPHA-FETOPROTEIN (AFP) TEST?

A globulin protein secreted by liver cells during hepatic cell multiplication and found in high amounts in fetal plasma. Highest adult amounts are found during pregnancy and in primary hepatic cancer. Maternal levels should be measured initially at 15-18 weeks of gestation as a screening method for fetal neural tube defects. Confirmatory testing (for levels greater than 0.5-2.5 times the normal median) should be repeated in 7 days. For the positive confirmatory test, ultrasonography and amniotic fluid AFP measurement should be performed. Used as a tumour marker, the AFP level is most specific when concentrations are >1000 ng/mL. 

 

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About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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