WHAT IS ALDOLASE TEST?
A group of isoenzymes (A, B, C) found throughout the body but in highest concentrations in skeletal muscle tissue, where aldolase is manufactured by myocytes. Because aldolase rises during active skeletal muscle disease, its measurement can help track the progress of diseases such as progressive muscular dystrophy, in which increases are seen in early stages, but levels fall as the disease progresses, reflecting lack of muscle ability to synthesise the aldolase enzyme. For most other muscle diseases, there are more specific tests available such as Creatine kinase— Serum; Alanine aminotransferase—Serum; and Aspartate aminotransferase—Serum. Norms for the isoenzymes are not established.