This medicine contains sertraline as active ingredient. It is an antidepressant drug that has a specific effect on certain areas of the brain. The medicine is known to affect serotonin, one of the chemicals in the brain called neurotransmitters or chemical messengers, that play a role in the steering of psychoactive behavior.
This medicine belongs to the group of selective serotonin reuptake inhibitors (SSRIs, which are chemically unrelated to other antidepressant drugs. These medicines prevent the movement of the neurotransmitter (chemical messenger between nerve cells) into nerve endings. This forces serotonin to remain in the spaces surrounding nerve endings, increasing its action.
Abnormal serotonin function may be involved in depression and relation brain disorders, and the selective serotonin reuptake inhibitors are effective in treating the common symptoms of depression and related cerebral disorders. For example, they can help improve mood and mental alertness, alleviate anxiety, and improve sleep patterns.
This medicine is prescribed for:
• Obsessive-compulsive disorder
• Panic disorder
• Social anxiety disorder
• Generalized anxiety disorder
• Posttraumatic stress disorder
Before using this medicine
Before you use this medicine check with your doctor, or pharmacist:
• if you ever had any unusual or allergic reaction to this medicine or any psychoactive drug;
• if you are allergic to any medicines, foods or other substances;
• if you are pregnant or intend to become pregnant while using this medicine (animal studies have shown toxic effects to developing fetuses);
• if you are breast-feeding an infant;
• if you have thought of suicide;
• if you have kidney or liver disease.
• This medication is used for treatment of certain types of mental depression, obsessive-compulsive disorders, and panic disorders.
• Usual dosage: The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regime. The recommended starting dose for adults is 50-100 mg. Depending on your response to this drug, your doses may be increased. Seniors and people with liver disease should take a lower dose. The medicine is not recommended for children.
• Tablets should be swallowed with liquid. If you forget to take a dose of this medicine, take it as soon as you remember up to two hours late. If more than two hours, wait for the next scheduled dose. In patients over 60 years of age, adverse reactions may be more frequent and severe than in younger persons.
• For safe and effective use of medicine: Follow your doctor’s instructions if this medicine was prescribed.
Along with the needed effects, a medicine may cause some unwanted effects. Possible side effects include:
Decreased sex drive
Cautions and Warnings
• Do not take this medicine if you are allergic or sensitive to any of their ingredients. Some people have experienced serious drug reactions to this type of medicine.
• This medicine can increase the risk of suicidal thinking and behavior in adults, children, and teens. Patients who are started on therapy should be observed closely for clinical worsening of depression, suicidality, or unusual changes in behavior, especially at the beginning of therapy, or when the dose is decreased or increased.
• The drug may affect platelets. although their exact effect is not known. Some people have had abnormal bleedings with taking this drug.
• This medicine should be used with caution by people with seizure disorders and in people with glaucoma.
• People with mania or hypomania may experience an activation or worsening of their condition taking this medicine, especially if they are not also taking an antimanic medication.
Driving or Hazardous Work
Do not drive until you learn how the medicine affects you. Do not work around dangerous machinery. Do not climb ladders or work in high places. Danger increases if you drink alcohol or take medicines affecting alertness and reflexes.
The following symptoms may be a sign of overdose:
Heart rhythm disturbances
Severe mouth dryness
• Call a doctor or hospital emergency room for instructions. If necessary, give first aid immediately.
The effect of this medicine may be increased by other antidepressants. Lithium, may increase the occurrence of side effects. Anticoagulants may cause an increase in anticoagulation. Alcohol will sometimes augment the depression.
• Be sure to tell your doctor about any medications you are currently taking.
The tablets should be stored at room temperature; store away from heat and direct light. Keep out of reach of children, since this medicine may be dangerous to children.