Seroquel

Seroquel

Properties

This medicine contains as active ingredient quetiapine, a psychoactive medicine that influences the activity of the brain; by affecting serotonin, histamine and dopamine, neurotransmitters in the brain, normalizing their chemical balance and relieving symptoms of   schizophrenia.

It is effective in reducing the violent aggressive manifestations of mental illnesses such as schizophrenia, mania, and other disorders in which hallucinations are experienced.

Prescribed for

The drug is prescribed for:

•   Schizophrenia

•   Psychotic behavior

•   Acute agitation in schizophrenia

•   Bipolar mania (both major and mixed episodes)

Before using this medicine

Before you use this medicine check with your  doctor:

•   if you ever had any unusual or allergic reaction to haloperidol.

•    if you are pregnant or intend to become pregnant while using this medicine. Decide with your doctor if the drug benefits justify the risk to the unborn child.

•    if you are breast-feeding an infant. The drug passes into the breast milk. Avoid the drug or discontinue nursing until you finish the medicine.

•   if you have suffering from a depression.

•   if you have Parkinson’s disease.

Cautions and Warnings

•    This medicine should not be used in people with dementia-related psychosis.

•    Antipsychotic drugs are often associated with involuntary uncoordinated, and uncontrolled movements. This reaction is most common among older adults, especially women. Contact your doctor if you develop any unusual movements while taking this medicine.

•    Neuroleptic malignant syndrome, a potentially fatal group of symptoms associated with this medicine and other psychoactive drugs, can occur. Important symptoms of this syndrome are:

•   High fever

•   Muscle rigidity

•   Mental changes

•   Irregular pulse

•   Rapid heartbeat

•   Sweating

•   Contact your doctor if you develop any of these side effects.

Treatment

This medication is used to relieve or prevent the symptoms of your medical problem affecting your brain  function.

Usual dose:The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your  doctor may prescribe a different regime. The starting dose for adults amounts to 150-250 milligrams a day. Some patients may need 500-750 milligrams a day. The drug is not recommended for children. Seniors may obtain maximum beneficial effects with smaller  doses.

Side Effects

Along with the needed effects, a medicine may cause some unwanted effects. Side effects may include:

Headache

Nausea

Agitation

Tiredness

Headache

Fainting

Dizziness

Abdominal pain

Weight gain

Upset stomach

Heart palpitations

Spastic movements

Difficulty talking

Sore throat

Running nose

Rash

Dry mouth

Appetite loss

Appetite loss

Sweating

Overdose

Symptoms of overdose are:

Weak, rapid pulse

Sedation

Slurring of speech

Rise in blood pressure

•    Call a doctor. Apply, if necessary, cardiac massage and mouth-to-mouth breathing.

Interactions

•   Some drugs to avoid are:

•   Ketoconazole

•   Itraconazole

•   Fluconazole

•   Erythromycin

•   Lorazepam

•    This drug can increase the effects of alcohol, sedatives, and other nervous system depressants.

•   Carbamazepine, phenobarbital, phenytoin, and rifampin may reduce the blood levels of this medicine.

•    Be sure to tell your doctor about any medications (also over-the-counter drugs) you are currently taking.

Driving or Hazardous Work

Do not drive until you learn how the medicine affects you. Do not work around dangerous machinery. Do not climb ladders or work in high places. Danger increases if you drink alcohol or take medicines affecting alertness and reflexes.

Storage

Store at room temperature in tightly closed, light-resistant containers. Keep out of the reach of children since overdose may be especially dangerous in children.

KNOWLEDGE BASE
About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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