UTERUS (ENDOMETRIUM AND MYOMETRIUM) MALIGNANCIES GENOMIC RISK ASSESSMENT

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Description

Description

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    WHAT IS UTERINE CANCER?
    • A woman’s uterus (womb), between the bladder and rectum, includes the cervix and the body. The cervix connects the uterus and vagina, and the body is connected to the fallopian tubes. Uterine cancer is cancer that grows in the lining of the uterus. Cancer can start from the cervix or the inner layer of the uterus (endometrium). It can also start from the body of the uterus; these rare tumours are uterine sarcomas.
    • Uterine cancer occurs most often in women who went through menopause (change of life).
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    WHAT CAUSES UTERINE CANCER?
    • The cause isn’t known, but many things can increase the risk. Diabetes, high blood pressure, taking the hormone estrogen without also using progesterone, and being very overweight may lead to higher risk.
    • Other conditions that increase risk are a family history of breast or ovarian cancer, uterine polyps, hormone imbalance, and going through menopause later than usual.
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    WHAT ARE THE SYMPTOMS OF UTERINE CANCER?
    • Early symptoms include bleeding and spotting, especially after sex. Watery or blood-streaked vaginal discharge can happen just before bleeding or spotting. Often bleeding occurs after periods have stopped for 12 months or more. The uterus may get larger, large enough to feel low in the abdomen (belly).
    • Later symptoms, after cancer spreads to other organs, include pain in the abdomen and chest and weight loss.
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    HOW IS UTERINE CANCER DIAGNOSED?
    • The doctor will make a diagnosis from the medical history, physical examination, and endometrial biopsy. In this biopsy, the doctor will take a tissue sample from the uterus and test it for cancer. Uterine cancer can spread to the bladder, rectum, and other organs. Other tests will be done to stage cancer—find out whether it has spread and how far. Tests include Pap smears, mammography, blood tests, computed tomography (CT), magnetic resonance imaging (MRI), ultrasonography, and scraping the uterine wall.
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    HOW IS UTERINE CANCER TREATED?
    • Treatment depends on cancer’s spread. Usually, the uterus and tumour, ovaries, and fallopian tubes will be removed in surgery.
    • Then radiotherapy, hormonal therapy, cortisone drugs, and chemotherapy may be used to shrink remaining cancer and prevent the spread of cancer. An oncologist (doctor specialising in cancer) will help in your care.
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    UTERUS (ENDOMETRIUM AND MYOMETRIUM) MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing uterus malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of uterus malignancies (i.e. first-degree relative who has been diagnosed with uterus malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.

    You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.

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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing uterus malignancy:

    EPCAM

    FH

    MLH1

    MSH2

    MSH6

    PMS2

    PTEN

    STK11

    TP53

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing uterus malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing uterus malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing uterus malignancy due to certain hereditary mutations in your genes.

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