THYROID MALIGNANCIES GENOMIC RISK ASSESSMENT

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SERVICE DESCRIPTION

SERVICE DESCRIPTION

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    WHAT IS THYROID CANCER?
    • The thyroid gland in the neck makes hormones that control metabolism. Cells in the thyroid gland are called follicular and parafollicular cells. Thyroid cancers are abnormal growths of these cells. These cancers start from either follicular cells (papillary, follicular, and anaplastic cancers) or parafollicular cells (medullary carcinoma). The papillary type is the most common. It occurs among young people. The follicular type occurs in older people. The medullary type can occur as isolated cancers or in families, as a hereditary form. The anaplastic type is aggressive and hard to treat.
    • About 10,000 new thyroid cancers are diagnosed each year in the United States.
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    WHAT CAUSES THYROID CANCER?
    • The cause is unknown. Radiation exposure is a risk for this cancer, especially in children who have radiation therapy to the head, neck, or upper chest during infancy or childhood. Thyroid cancer isn’t contagious.
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    WHAT ARE THE SYMPTOMS OF THYROID CANCER?
    • Usually, a thyroid nodule (lump) is the first symptom. As the cancers grow, they usually spread to nearby areas and cause hoarseness, trouble swallowing, swollen lymph glands, and neck pain.
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    HOW IS THYROID CANCER DIAGNOSED?
    • The doctor may suspect thyroid cancer by finding a lump on the thyroid during a physical examination. For proof of cancer, cells are taken from the lump by fine-needle aspiration biopsy (FNAB) and studied with a microscope. In this type of biopsy, the doctor uses a needle to get a sample.
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    HOW IS THYROID CANCER TREATED?
    • Treatment can be surgery, radiation therapy, or chemotherapy. Type of treatment depends on whether cancer has spread.
    • Removal of the thyroid, either part or the whole gland, is called thyroidectomy. Complications of surgery include injury to vocal cords.
    • If the whole thyroid is removed, thyroid replacement medicine is taken for the rest of life. If an only part is removed, the hormone may also be given to stop the growth of remaining thyroid tissue.
    • Radioactive iodine can be used after surgery or to treat the spread of cancer. Radioactive iodine kills normal and cancer cells.
    • Chemotherapy is used if other treatments don’t work.
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    THYROID MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing thyroid malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of thyroid malignancies (i.e. first-degree relative who has been diagnosed with thyroid malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing thyroid malignancy:

    APC

    CHEK2

    DICER1

    MEN1

    PRKAR1A

    PTEN

    RET

    TP53

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing thyroid malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing thyroid malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing thyroid malignancy due to certain hereditary mutations in your genes.

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