OVARIES MALIGNANCIES GENOMIC RISK ASSESSMENT

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SERVICE DESCRIPTION

SERVICE DESCRIPTION

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    WHAT IS OVARIAN CANCER?
    • Ovarian cancer is a malignant tumour in the ovary, the woman’s reproductive organ that releases eggs and female hormones, such as estrogen. It’s the second most common women’s cancer (after cancer of the uterus). About half of women with this cancer are older (average age of 59) and have gone through menopause (change of life), so their ovaries no longer work.
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    WHAT CAUSES OVARIAN CANCER?
    • The cause isn’t clear, but certain things can increase the chances of getting it. The most important are age and having relatives who had it. Others are obesity, having breast cancer, starting periods early, and going through menopause late. Some other factors, such as having children, breastfeeding, and using birth control pills, can lower the chances.
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    WHAT ARE THE SYMPTOMS OF OVARIAN CANCER?
    • The most common symptoms are vague or mild and include discomfort or a heavy feeling in the lower abdomen (belly), loss of appetite, and weight loss or gain. Others are abnormal periods, back pain, nausea, and loss of appetite.
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    HOW IS OVARIAN CANCER DIAGNOSED?
    • The doctor may suspect cancer because of symptoms and physical examination. Imaging tests (such as ultrasonography) can suggest the possibility of cancer. A biopsy is the only way to tell whether a mass in the ovary is cancer. In a biopsy, a small piece of tissue is surgically removed and studied with a microscope. The doctor also uses the surgery to find out the stage (extent) of cancer. The stage relates to how far cancer spread. Sometimes, tumour markers (CA-125, a substance found in the blood) may help diagnosis.
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    HOW IS OVARIAN CANCER TREATED?
    • Treatment depends on the location and stage of the disease, type of cancer, and age and general health. The main treatment is surgery, usually to remove ovaries, fallopian tubes, lymph glands (nodes), and uterus. Special doctors called gynecologic oncologists are the best doctors for treatment.
    • Drugs (chemotherapy) and radiation therapy are other choices.
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    OVARIES MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing ovaries malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of ovaries malignancies (i.e. first-degree relative who has been diagnosed with ovaries malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing ovaries malignancy:

    BRCA1

    BRCA2

    BRIP1

    DICER1

    EPCAM

    MLH1

    MSH2

    MSH6

    PALB2

    PMS2

    PPM1D

    RAD51C

    RAD51D

    STK11

    TP53

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing ovaries malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing ovaries malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing ovaries malignancy due to certain hereditary mutations …

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