LUNG & PLEURA MALIGNANCIES GENOMIC RISK ASSESSMENT

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Description

Description

  1. 1
    WHAT IS LUNG CANCER?
    • Lung cancer occurs when cells in the lung grow out of control and form a mass. Nearly 90% of lung cancers start in the lining of air passages or air sacs. Air passages are tubes called bronchi (main tubes) and bronchioles (smaller tubes). Air sacs (alveoli) are at the ends of the tubes.
    • Lung cancer is usually divided into two types: non—small cell and small cell.
    • Lung cancer is one of the most common cancers among both men and women. Every year, more than 170,000 new cases are diagnosed in the United States.
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    WHAT CAUSES LUNG CANCER?
    • Almost 90% of lung cancers occur among smokers or former smokers. Therefore, the use of tobacco (cigarettes, cigars, pipes) is the main cause.
    • Other causes include exposure to asbestos (especially for smokers), radon and radiation, and secondhand smoke (other people’s smoke).
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    WHAT ARE THE SYMPTOMS OF LUNG CANCER?
    • Some people may have no symptoms until the cancer is advanced.
    • In others, symptoms include a cough that doesn’t go away, coughing up bloody phlegm, shortness of breath, wheezing, continuing problems with pneumonia, tiredness, difficulty swallowing, loss of appetite, and weight loss.
    • A tumour may press on a large blood vessel, which causes swelling of the face and neck (called superior vena cava syndrome).
    • A tumour pressing on nerves near the lung can lead to pain in the shoulder, arm, and hand (called Pancoast’s tumour).
    • Some types of lung cancer can produce certain chemicals (hormones) that lead to abnormal blood test results, such as a high calcium level; weakness; and other problems (e.g., Lambert-Eaton syndrome, clubbing of fingers or toes, and syndrome of inappropriate secretion of antidiuretic hormone [ SIADI-1]).
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    HOW IS LUNG CANCER DIAGNOSED?
    • Early diagnosis can be hard because people may have no symp¬toms until the cancer is advanced. In these people, a tumour may be found on a routine chest x-ray or computed tomography (CT) scan.
    • The only sure way to diagnose lung cancer is by taking and studying a sample of lung tissue (biopsy) or fluid from the lungs that contains cancer cells.
    • The doctor gets these samples in different ways, depending on the location of the problem area. One technique is bronchoscopy, or examination with a lighted scope (a thin, flexible tube) that passes through the mouth into the air passages. If this method doesn’t work, needle aspiration can be done. In this procedure, a needle is passed through the chest into the tumour to get the cells.
    • Sometimes, the space surrounding the lungs has fluid in it. This fluid can be removed with a needle (thoracentesis) to check for cancer cells.
    • If none of these techniques works, surgery (thoracotomy) can be done to open the chest and get tissue samples directly.
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    LUNG & PLEURA MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing lung & pleura malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of lung & pleura malignancies (i.e. first-degree relative who has been diagnosed with lung & pleura malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing lung & pleura malignancy:

    BAP1

    DICER1

    EGFR

  7. 7
    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing lung & pleura malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing lung & pleura malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
  8. 8
    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

  9. 9
    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

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£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing lung & pleura malignancy due to certain hereditary mutations ….

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