LIVER MALIGNANCIES GENOMIC RISK ASSESSMENT

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Description

Description

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    WHAT IS LIVER CANCER?
    • Hepatoma (also called hepatocellular carcinoma) is the most common cancer of the liver. It’s a primary tumour, meaning the tumour started growing in the liver and did not spread from someplace else in the body.
    • In the United States, about 6000 new cases occur each year. Hepatomas are more common in men than women, usually occurring in people 50 to 70 years old. Unfortunately, many hepatomas are found late. Early diagnosis gives the best hope for a cure.
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    WHAT CAUSES LIVER CANCER?
    • Hepatoma occurs most often in people with cirrhosis (liver scarring), chronic hepatitis B, or chronic hepatitis C or after severe liver damage from chronic alcohol abuse. Hepatomas aren’t contagious or passed from parents to children.
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    WHAT ARE THE SYMPTOMS OF LIVER CANCER?
    • One-third of people do not have any symptoms. Symptoms may include pain in the abdomen (belly), an abdominal mass, abdominal fluid (ascites), and jaundice (yellow skin colour). Later, weakness, loss of appetite, weight loss, and fatigue can occur.
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    HOW IS LIVER CANCER DIAGNOSED?
    • Diagnosis is difficult because hepatomas often don’t have many early symptoms. To help diagnosis, the doctor may initially do blood tests called alpha-fetoprotein and liver function tests for people with cirrhosis or hepatitis B or C. However, these tests are not diagnostic because not everyone with a hepatoma has abnormal blood tests, so the doctor may want imaging studies called ultrasound, computed tomography (CT), or magnetic resonance imaging (MRI). If these imaging studies show a probable tumour, a liver biopsy will be done. In a biopsy, liver tissue is taken with a needle and looked at with a microscope.
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    HOW IS LIVER CANCER TREATED?
    • Untreated people have a rapid downhill course. Surgery offers the best chance for a cure, but most people cannot have surgery because of cirrhosis or tumour spread. Smaller tumours (less than 5 cm, or about 2 inches) that haven’t spread and with remaining liver working well are less likely to recur after surgery.
    • People who cannot have surgery may have other treatments, including injecting chemotherapy drugs into the artery that feeds the tumour or injecting ethanol (alcohol) directly into the tumour to destroy it.
    • People with very large tumours or with too much liver damage may be candidates for liver transplantation. A team of doctors and other health care workers must work together to manage care.
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    LIVER MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing liver malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of liver malignancies (i.e. first-degree relative who has been diagnosed with liver malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

     This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing liver malignancy:

    APC

    HNF1A

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing liver malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing liver malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing liver malignancy due to certain hereditary mutations in your genes.

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