KIDNEY MALIGNANCIES GENOMIC RISK ASSESSMENT

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SERVICE DESCRIPTION

SERVICE DESCRIPTION

  1. 1
    WHAT ARE THE SYMPTOMS OF KIDNEY CANCER?
    • Early disease may cause no symptoms. As the tumour grows, symptoms may include blood in the urine, lump or mass in the kidney area, tiredness, loss of appetite, weight loss, fevers, and pain in the abdomen (belly).
  2. 2
    HOW IS KIDNEY CANCER DIAGNOSED?
    • The doctor makes a diagnosis by special x-rays, including computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography. The only way to confirm the diagnosis is with a biopsy. For a biopsy, the doctor removes a small piece of the kidney and checks it with a microscope. CT or MRI is also used to learn the stage or extent of disease, which helps plan treatment. Staging tells the doctor whether cancer has spread and if so, how far, such as to lymph nodes (glands) or lungs.
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    HOW IS KIDNEY CANCER TREATED?
    • The most common treatment is an operation to remove the kidney (nephrectomy). The whole kidney, adrenal gland, tissue around the kidney, and lymph nodes may be removed. A procedure called arterial embolisation may be used to shrink the tumour. It blocks the main blood vessel to the kidney, so the tumour doesn’t get the oxygen-carrying blood and other substances that it needs to grow.
    • Radiation therapy (or radiotherapy) uses high-energy radiation to kill cancer cells. It can also be used to relieve pain (as palliative therapy) when kidney cancer spread to bones.
    • Chemotherapy (drugs for killing cancer cells) is generally not very helpful against kidney cancer. Immunotherapy involves the use of biological agents such as interferon, sunitinib, and bevacizumab. It is a newer treatment modality that has shown some success in the treatment of advanced kidney cancer.
  4. 4
    KIDNEY MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing kidney malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of kidney malignancies (i.e. first-degree relative who has been diagnosed with kidney malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
  5. 5
    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing kidney malignancy:

    BAP1

    BUB1B

    CEP57

    DICER1

    DIS3L2

    FH

    FLCN

    MET

    PTEN

    SDHB

    SDHC

    SDHD

    SMARCB1

    TSC1

    TSC2

    VHL

    WT1

  6. 6
    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing kidney malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing kidney malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
  7. 7
    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

  8. 8
    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
  9. 9
    FREQUENTLY ASKED QUESTIONS
  10. 10
    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing kidney malignancy due to certain hereditary mutations in your genes.

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