BRAIN MALIGNANCIES GENOMIC RISK ASSESSMENT

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SERVICE DESCRIPTION

SERVICE DESCRIPTION

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    WHAT IS BRAIN CANCER?
    • Brain cancer is a malignant cell growth in the brain. The cancer can be primary (75%), meaning that it started in the brain, or secondary (25%), meaning that it spread from another part of the body to the brain. About 40% of brain cancers start from glial cells and are named gliomas. Gliomas include astrocytomas, glioblastomas, oligodendrogliomas, ependymomas, and medulloblastomas. The most common secondary cancers spread from cancers of the breast, lung, kidney, colon, and skin (melanoma).
    • Primary brain tumors can affect anyone but are more common in children younger than 15 and in middle-aged adults. Secondary brain tumors are more common in adults.
    • Brain cancer cannot be prevented. Most primary brain tumors, if found early, can be cured.
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    WHAT CAUSES BRAIN CANCER?
    • The cause of primary brain tumours is unknown.
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    WHAT ARE THE SYMPTOMS OF BRAIN CANCER?

    Headaches and seizures are the most common symptoms. Headaches usually occur in the early morning, sometimes waking people up, and worsen with coughing or sneezing. The growing tumour pressing up against the skull causes the headaches. Other symptoms depend on the location of the tumour but can include behaviour changes, confusion, and trouble with speech, memory, or concentration.

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    HOW IS BRAIN CANCER DIAGNOSED?

    Magnetic resonance imaging (MRI) is usually used to find cancer. Computed tomography (CT) can also be used. The only way to prove the diagnosis is to take a tissue sample from the tumour and study it under the microscope. Taking this sample can be done either by a biopsy or at the surgery if the whole tumour is to be removed.

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    HOW IS BRAIN CANCER TREATED?
    • Primary brain tumours are usually removed. Depending on the tumour type and location, surgery gives the best chance for a cure if the whole tumour can be removed. Surgery also allows diagnosis of the type of cancer and relieves pressure in the brain.
    • Radiation therapy, another treatment method, is performed by specialists (radiation oncologists) and is usually used for tumours that cannot be removed (or removed completely), or after surgery for any brain cancer.
    • Chemotherapy is not often used for primary brain tumours.
    • An antiseizure medicine, such as phenytoin, is often used before and after surgery. For swelling in the brain, the doctor may prescribe a steroid (dexamethasone).
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    BRAIN MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing brain malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of brain malignancies (i.e. first-degree relative who has been diagnosed with brain malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing brain malignancy:

    AIP

    APC

    CDKN1C

    CDKN2A

    DICER1

    GPC3

    MLH1

    MSH2

    MSH6

    NBN

    NF2

    PMS2

    PRKAR1A

    PTCH1

    PTEN

    SMARCA4

    SMARCB1

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing brain malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing brain malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing brain malignancy due to certain hereditary mutations in your genes.

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