BLADDER MALIGNANCIES GENOMIC RISK ASSESSMENT

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Description

Description

  1. 1
    WHAT IS BLADDER CANCER?
    • The bladder is the organ that stores urine before it leaves the body. The bladder lining consists of transitional cells. Nearly 95% of all bladder cancers start from these cells (transitional cell carcinoma). Bladder cancer is a malignant tumour in this organ and may be small or large, growing deep into the bladder muscle, and it may spread (metastasise).
    • The other two types are squamous carcinoma and adenocarcinoma. These tumours are usually larger and often go into the bladder wall and may metastasise.
    • Bladder cancer develops most often in people older than 50. Men have bladder cancer more often than women do.
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    WHAT CAUSES BLADDER CANCER?
    • Very small cancers usually cause no symptoms, but blood in the urine, burning when urinating, or needing to urinate small amounts are possible symptoms.
    • Larger tumours cause more symptoms, such as pain low in the belly or losing weight.
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    HOW IS BLADDER CANCER DIAGNOSED?
    • The doctor will do an examination and order a urine test to see if the urine shows blood, signs of infection, or abnormal (cancerous) cells.
    • The doctor may also order blood tests and tests of the kidneys and liver function.
    • X-rays of the bladder and urinary tract, ultrasound or computed tomography (CT) scans, and cystoscopy (using a lighted tube to see inside the bladder) may also be done. If abnormal areas are found, a piece of tissue (biopsy specimen) is taken for study under a microscope.
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    HOW IS BLADDER CANCER TREATED?
    • Surgery is needed to remove cancer. The operation depends on the type of cancer and whether it has spread.
    • A small or large tumour is removed by endoscopy (using a lighted tube inserted into the bladder). For a very large cancer, the whole bladder may need to be taken out (radical cystectomy). After this operation, urine will empty out through a pouch through the skin (urostomy), which needs special care.
    • Pain pills, radiation treatment, and anticancer medicine (chemotherapy) may also be needed.
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    BLADDER MALIGNANCIES GENOMIC RISK ASSESSMENT
    • Innovative genomic DNA testing to investigate if you are at a higher risk of developing bladder malignancy due to certain hereditary mutations in your genes.
    • This genomic test is recommended if you have a strong family history of bladder malignancies (i.e. first-degree relative who has been diagnosed with bladder malignancy).
    • You will be provided with a DNA assessment kit that contains all the necessary materials and instructions to have your DNA sample taken without any pain or stress.
    • You will be able to take your DNA sample in the comfort of your home (or you can get your treating GP or specialist to take it for you in the clinic). Afterwards, you can simply post the DNA sample back, in the provided prepaid envelope, to Genomic Medicine UK laboratory in London.
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    OVERVIEW

    This genomic malignancy risk assessment evaluates your DNA for the following hereditary genetic mutations that may increase your risk of developing bladder malignancy:

    HRAS

    MLH1

    MSH2

    MSH6

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    KNOWLEDGE IS POWER
    • If your results show that you are genetically predisposed to developing bladder malignancy, your prognosis will be significantly improved by having regular malignancy screenings at shorter intervals. Please remember that the absolute majority of malignant tumours are treatable and curable when they are caught at their early stages.
    • If your test shows that you are at a higher risk of developing bladder malignancy, this can be enormously mitigated in most of the cases by adopting a healthier lifestyle and following our malignancy prevention guidance. Please remember that genes are not a destiny book but are only a background for a multitude of different potentials.
    • It is always true that prevention is better than cure.
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    FREE REFERRAL TO A SPECIALIST CONSULTANT

    If you your genomic testing showed that you require referral to a specialist consultant, we will provide you, at no cost to you, with a referral letter to a specialist consultant from our wide network of independent doctors all around the United Kingdom. Our referral letter will give the specialist consultant all the needed details to take care of your clinical case, according to the results of the genomic tests you have had at Genomic Medicine UK.

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    QUALITY ASSURANCE
    • This advanced genomic test is carried out by cutting-edge next-generation DNA sequencing technology at our ISO9000 certified and accredited laboratory.
    • All test results are interpreted and reported in London by our highly qualified licenced consultant medical doctors.
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    FREQUENTLY ASKED QUESTIONS
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    FURTHER INFORMATION
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    SAMPLE REPORTS
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    BY POST OR BY APPOINTMENT

    If you prefer to visit Genomic Medicine UK instead of having your genomic test by post, as explained above, you are most welcome to book a suitable appointment for you to visit our premises in central London where our fully trained and friendly staff will be more than happy to take your DNA sample in one of our outpatients’ clinics in Harley Street.

£499.00

£499.000

Innovative genomic DNA testing to investigate if you are at a higher risk of developing bladder malignancy due to certain hereditary mutations ….

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