This medicine contains nortriptyline as active ingredient. It belongs to the group of medicines known as tricyclic antidepressants or “mood elevators.” Tricyclic antidepressants block the passage of stimulant chemicals – norepinephrine and/or serotonin – in and out of nerve endings, producing a tranquillizing or sedative effect. They also counteract the effects of the neurotransmitter acetylcholine.

Such medicines work by causing long-term changes in the way nerve endings release specific neurotransmitters, that are responsible for the transmission of nerve signals. Tricyclic antidepressants can elevate mood, increase physical activity and mental alertness, and improve appetite and sleep patterns after 2-4 weeks of use.

Prescribed for

The medicine is prescribed for:

•   Relieve of mental depression

•   Depression that sometimes occurs with anxiety

•   Narcolepsy

•   Bulimia

•   Panic attacks

•   Cocaine withdrawal syndrome

The medication gradually relieves, but does not cure, symptoms of depression.

Before using this medicine

Before you use this medicine check with your doctor, or  pharmacist:

•    if you ever had any unusual or allergic reaction to any tricyclic antidepressant, maprotiline or trazodone.

•    if you are on a low-salt, low-sugar, or any other special diet, or if you are allergic to any substance, such as sulfites or other preservatives or dyes.

•    if you are pregnant or intend to become pregnant while using this medicine. There have been reports of newborns suffering from heart, breathing, and urinary problems when their mothers had taken tricyclic antidepressants before delivery.

•    if you are breast-feeding an infant. Some tricyclic antidepressants pass into the breast milk.


•    Take this medicine only as directed by your doctor, to benefit your condition as much as possible. Do not take more of it, do not take it more often, and do not take it for a longer period of time than your doctor ordered.

•    Usual dosage: The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regime. Adult: 25 mg 3-4 times a day; increased to 125 mg a day if necessary. Senior and child (age 14 and over): 30-50 mg a day.

•    Sometimes this medicine must be taken for several weeks before you begin to feel better.

Side Effects

Along with the needed effects, a medicine may cause some unwanted effects. Side effects that usually do not require medical attention: difficult or frequent urination; decreased sex drive; muscle aches; abnormal dreams; nasal congestion; weakness and faintness when arising from bed or chair.

•    Other side effects that should be reported to your doctor immediately are:



Dizziness or fainting

Blurred vision, eye pain

Irregular heartbeat or slow pulse

Inflamed tongue

Abdominal pain


Hair loss, rash

Fever, chills

Joint pain



This medicine may interact with several other drugs such as anticoagulants, anticholinergics, cold remedies, oral  contraceptives, seizure medicines, sleeping medicines, thyroid medicines,  etc.

•    Be sure to tell your doctor about any medications you are currently taking.

Driving or Hazardous Work

Do not drive until you learn how the medicine affects you. Do not work around dangerous machinery. Do not climb ladders or work in high places. Danger increases if you drink alcohol or take medicines affecting alertness and reflexes.


Tablets, capsules, etc. should be stored at room temperature in tightly closed, light-resistant containers as directed by your pharmacist. Keep out of reach of children since overdose is especially dangerous in young children. Do not store in the bathroom medicine cabinet because the heat or moisture may cause the medicine to break down. Keep the liquid form of the medicine from freezing.

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