How does the prostate cancer genetic test work?
Prostate Cancer Genetic Testing is performed on a blood or saliva sample and it takes 4-6 weeks to obtain the results. Prostate Cancer Genetic Testing uses state of the art Next Generation Sequencing to examine the code for each of the 8 genes in detail. In addition, dosage analysis is used to look for large deletions (missing parts) and duplications (extra parts) in the genes. However, no test is 100% accurate and it is possible that someone could have a genetic mutation which is not detected by this test. It is important to be aware that a normal result on Prostate Cancer Genetic Testing does not rule out the risk of hereditary prostate cancer. Where possible, it is most accurate to perform genetic testing on someone who has had cancer so that a possible genetic cause can be found in the family.
HOXB13: This gene has been found in 5% of prostate cancer families and causes an estimated 3-5 fold increased risk of prostate cancer.