Buproprion

Buproprion

Properties

This medicine contains buproprion as active ingredient. It is an psychactive drug that has a specific effect on certain areas of the brain. The medicine works primarily on dopamine and noradrenaline, essential neurotransmitters of nerve cells in the brain. The neurotransmitters are of vital importance in transmitting neural signals. The medicine may not act until you have taken it for 2-4 weeks. The medicine clears your system about two weeks after you stop taking it.

Indications

This medicine is prescribed for:

  • Depression
  • Seasonal affective disorder
  • Nicotine addiction

Before using this medicine

Before you use this medicine check with your doctor, or  pharmacist:

  • if you ever had any unusual or allergic reaction to this medicine or any psychoactive drug;
  • if you are allergic to any medicines, foods or other substances;
  • if you are pregnant or intend to become pregnant while using this medicine (animal studies have shown toxic effects to developing fetuses);
  • if you are breast-feeding an infant;
  • if you have thought of suicide;
  • if you have kidney or liver disease.

Treatment

Usual dosage:The information below is based on the dosage guidelines your doctor uses. Depending on your condition and medical history, your doctor may prescribe a different regime. The recommended starting dose for adults is 200-450 mg a day; normal daily dosage is 300 mg. The medicine is not recommended for children.

Warnings and Cautions

  • Antidepressants have been associated with an increased risk of suicide, especially in children and teenagers. Suicide is always a risk in depressed people, who should only be allowed to have minimal quantities of medication in their Clinical worsening of a depressed person’s condition may also occur in therapy with antidepressants.
  • People with seizure disorders, people who have had a seizure in the past and people with bulimia or anorexia nervosa, should be very careful about taking this medication because they are at higher risk of having a seizure.
  • People with unstable heart disease or those who have had a recent heart attack should take this medicine with caution because of possible side effects.

Side Effects

Along with the needed effects, a medicine may cause some unwanted effects. Possible side effects include:

  • Headache
  • Nervousness
  • Dizziness
  • Increased sweating
  • Nausea
  • Insomnia
  • Sedation
  • Agitation
  • Sleeplessness
  • Tremors
  • Upset stomach
  • Increased appetite
  • Menstrual complaints
  • Decreased sex drive
  • Impotence
  • Dry mouth

Driving or Hazardous Work

Do not drive until you learn how the medicine affects you. Do not work around dangerous machinery. Do not climb ladders or work in high places. Danger increases if you drink alcohol or take medicines affecting alertness and reflexes.

Overdosage

The following symptoms may be a sign of overdose:

  • Seizures
  • Hallucinations
  • Loss of consciousness
  • Abnormal heart rhythm

Call a doctor or hospital emergency room for instructions. If necessary, give first aid immediately.

Interactions

The effect of this medicine may be increased by other psychoactive medicines. Be sure to tell your doctor about any medications you are currently taking.

Storage

The tablets should be stored at room temperature. Keep out of reach of children, since this medicine may be dangerous to  children.

KNOWLEDGE BASE
About Genomic Medicine UK

Genomic Medicine UK is the home of comprehensive genomic testing in London. Our consultant medical doctors work tirelessly to provide the highest standards of medical laboratory testing for personalised medical treatments, genomic risk assessments for common diseases and genomic risk assessment for cancers at an affordable cost for everybody. We use state-of-the-art modern technologies of next-generation sequencing and DNA chip microarray to provide all of our patients and partner doctors with a reliable, evidence-based, thorough and valuable medical service.

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